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Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

Many epithelial cancers show cell cycle dysfunction tightly correlated with the overexpression of the serine/threonine kinase Aurora A (AURKA). Its role in mitotic progression has been extensively characterised, and evidence for new AURKA functions emerges. Here, we reveal that AURKA is located and...

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Detalles Bibliográficos
Autores principales: Bertolin, Giulia, Bulteau, Anne-Laure, Alves-Guerra, Marie-Clotilde, Burel, Agnes, Lavault, Marie-Thérèse, Gavard, Olivia, Le Bras, Stephanie, Gagné, Jean-Philippe, Poirier, Guy G, Le Borgne, Roland, Prigent, Claude, Tramier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140714/
https://www.ncbi.nlm.nih.gov/pubmed/30070631
http://dx.doi.org/10.7554/eLife.38111