The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation and deleterious cell fate decisions remain unclear. Here we sh...

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Detalles Bibliográficos
Autores principales: Li, Bo, Wong, Chouin, Gao, Shihong Max, Zhang, Rulan, Sun, Rongbo, Li, Yulong, Song, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140715/
https://www.ncbi.nlm.nih.gov/pubmed/30176986
http://dx.doi.org/10.7554/eLife.38181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140715/
https://www.ncbi.nlm.nih.gov/pubmed/30176986
http://dx.doi.org/10.7554/eLife.38181

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