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The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking
The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation and deleterious cell fate decisions remain unclear. Here we sh...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140715/ https://www.ncbi.nlm.nih.gov/pubmed/30176986 http://dx.doi.org/10.7554/eLife.38181 |