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SOX5 induces lung adenocarcinoma angiogenesis by inducing the expression of VEGF through STAT3 signaling

BACKGROUND AND OBJECTIVES: Angiogenesis is the main cause of lung adenocarcinoma (LAC) poor prognosis. This study aimed to investigate the effect of sex-determining region Y-box protein 5 (SOX5) expression on angiogenesis of LAC and explore its possible mechanism. PATIENTS AND METHODS: The effect on...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Zheng, Qi, Li, Weidong, Lu, Yuan, Ni, Yiming, Ma, Liang, Fu, Yufei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140741/
https://www.ncbi.nlm.nih.gov/pubmed/30254466
http://dx.doi.org/10.2147/OTT.S176533