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Functional characteristics of novel pancreatic Pax6 regulatory elements

Complex diseases, such as diabetes, are influenced by comprehensive transcriptional networks. Genome-wide association studies have revealed that variants located in regulatory elements for pancreatic transcription factors are linked to diabetes, including those functionally linked to the paired box...

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Detalles Bibliográficos
Autores principales: Buckle, Adam, Nozawa, Ryu-suke, Kleinjan, Dirk A, Gilbert, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140780/
https://www.ncbi.nlm.nih.gov/pubmed/30007277
http://dx.doi.org/10.1093/hmg/ddy255