Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk

Osteoarthritis (OA) is a common, multifactorial and polygenic skeletal disease that, in its severest form, requires joint replacement surgery to restore mobility and to relieve chronic pain. Using tissues from the articulating joints of 260 patients with OA and a range of in vitro experiments, inclu...

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Detalles Bibliográficos
Autores principales: Rice, Sarah J, Aubourg, Guillaume, Sorial, Antony K, Almarza, David, Tselepi, Maria, Deehan, David J, Reynard, Louise N, Loughlin, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140783/
https://www.ncbi.nlm.nih.gov/pubmed/30010910
http://dx.doi.org/10.1093/hmg/ddy257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140783/
https://www.ncbi.nlm.nih.gov/pubmed/30010910
http://dx.doi.org/10.1093/hmg/ddy257

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