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Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk
Osteoarthritis (OA) is a common, multifactorial and polygenic skeletal disease that, in its severest form, requires joint replacement surgery to restore mobility and to relieve chronic pain. Using tissues from the articulating joints of 260 patients with OA and a range of in vitro experiments, inclu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140783/ https://www.ncbi.nlm.nih.gov/pubmed/30010910 http://dx.doi.org/10.1093/hmg/ddy257 |