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Dynamic evaluation of the immune infiltrate and immune function genes as predictive markers for neoadjuvant chemotherapy in hormone receptor positive, HER2 negative breast cancer

Gene expression (GE) signatures and Tumor Infiltrating Lymphocytes (TIL) enumeration are predictive for response to neoadjuvant chemotherapy in HR- and in HER2+ breast cancer, but data are conflicting in HR+/HER2- disease. This study aimed to explore their predictive value in this subset, measured b...

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Detalles Bibliográficos
Autores principales: Matikas, Alexios, Lövrot, John, Ramberg, Anna, Eriksson, Margareta, Lindsten, Therese, Lekberg, Tobias, Hedenfalk, Ingrid, Loman, Niklas, Bergh, Jonas, Hatschek, Thomas, Erlandsson, Ann, Foukakis, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140817/
https://www.ncbi.nlm.nih.gov/pubmed/30228933
http://dx.doi.org/10.1080/2162402X.2018.1466017