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The Shieldin complex mediates 53BP1-dependent DNA repair

53BP1 is a chromatin-binding protein that regulates DNA double-strand break (DSB) repair by suppressing the nucleolytic resection of DNA termini1,2. This function of 53BP1 requires interactions with PTIP3 and RIF14–9, the latter also recruiting REV7/MAD2L2 to break sites10,11. How 53BP1-pathway prot...

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Detalles Bibliográficos
Autores principales:	Noordermeer, Sylvie M., Adam, Salomé, Setiaputra, Dheva, Barazas, Marco, Pettitt, Stephen J., Ling, Alexanda K., Olivieri, Michele, Álvarez-Quilón, Alejandro, Moatti, Nathalie, Zimmermann, Michal, Annunziato, Stefano, Krastev, Dragomir B., Song, Feifei, Brandsma, Inger, Frankum, Jessica, Brough, Rachel, Sherker, Alana, Landry, Sébastien, Szilard, Rachel K., Munro, Meagan M., McEwan, Andrea, Goullet de Rugy, Théo, Lin, Zhen-Yuan, Hart, Traver, Moffat, Jason, Gingras, Anne-Claude, Martin, Alberto, van Attikum, Haico, Jonkers, Jos, Lord, Christopher J., Rottenberg, Sven, Durocher, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141009/ https://www.ncbi.nlm.nih.gov/pubmed/30022168 http://dx.doi.org/10.1038/s41586-018-0340-7

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