Inhibitor of IGF1 receptor alleviates the inflammation process in the diabetic kidney mouse model without activating SOCS2

OBJECTIVE: To explore the anti-inflammatory mechanism of IGF1R inhibitor in diabetic nephropathy. METHODS: C57/BL6 mice were reared with high-fat diet for 8 weeks, then were injected 30 mg/kg streptozotocin intraperitoneally to induce type 2 diabetes. After 8 weeks, the type 2 diabetes nephropathy m...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jiayu, Dong, Rong, Yu, Jiali, Yi, Sun, Da, Jingjing, Yu, Fuxun, Zha, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141121/
https://www.ncbi.nlm.nih.gov/pubmed/30254418
http://dx.doi.org/10.2147/DDDT.S171638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141121/
https://www.ncbi.nlm.nih.gov/pubmed/30254418
http://dx.doi.org/10.2147/DDDT.S171638

Ejemplares similares