PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN

Centrosome structure, function, and number are finely regulated at the cellular level to ensure normal mammalian development. Here, we characterize PPP1R35 as a novel bona fide centrosomal protein and demonstrate that it is critical for centriole elongation. Using quantitative super-resolution micro...

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Detalles Bibliográficos
Autores principales: Sydor, Andrew Michael, Coyaud, Etienne, Rovelli, Cristina, Laurent, Estelle, Liu, Helen, Raught, Brian, Mennella, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141234/
https://www.ncbi.nlm.nih.gov/pubmed/30168418
http://dx.doi.org/10.7554/eLife.37846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141234/
https://www.ncbi.nlm.nih.gov/pubmed/30168418
http://dx.doi.org/10.7554/eLife.37846

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