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Silencing of quinolinic acid phosphoribosyl transferase (QPT) gene for enhanced production of scopolamine in hairy root culture of Duboisia leichhardtii

Scopolamine is a pharmaceutically important tropane alkaloid which is used therapeutically in the form of an anesthetic and antispasmodic drug. The present study demonstrates enhanced scopolamine production from transgenic hairy root clones of Duboisia leichhardtii wherein the expression of quinolin...

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Detalles Bibliográficos
Autores principales: Singh, Pooja, Prasad, Ratnum, Tewari, Rashi, Jaidi, Meraj, Kumar, Susheel, Rout, P. K., Rahman, Laiq ur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141460/
https://www.ncbi.nlm.nih.gov/pubmed/30224763
http://dx.doi.org/10.1038/s41598-018-32396-0