Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood

Cannabis use is typically initiated during adolescence and is a significant risk factor for the development of cocaine use in adulthood. However, no preclinical studies have examined the effects of adolescent cannabinoid exposure on cocaine dependence in adulthood using the escalation model of cocai...

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Detalles Bibliográficos
Autores principales: Kononoff, Jenni, Melas, Philippe A., Kallupi, Marsida, de Guglielmo, Giordano, Kimbrough, Adam, Scherma, Maria, Fadda, Paola, Kandel, Denise B., Kandel, Eric R., George, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141462/
https://www.ncbi.nlm.nih.gov/pubmed/30224774
http://dx.doi.org/10.1038/s41598-018-31921-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141462/
https://www.ncbi.nlm.nih.gov/pubmed/30224774
http://dx.doi.org/10.1038/s41598-018-31921-5

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