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Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells

Intestinal epithelial tight junctions (TJ) are a major barrier restricting the entry of various harmful factors including pathogens; however, they also represent an important entry portal for pathogens. Although the rotavirus-induced early disruption of TJ integrity and targeting of TJ proteins as c...

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Detalles Bibliográficos
Autores principales: Soliman, Mahmoud, Cho, Eun-Hyo, Park, Jun-Gyu, Kim, Ji-Yun, Alfajaro, Mia Madel, Baek, Yeong-Bin, Kim, Deok-Song, Kang, Mun-Il, Park, Sang-Ik, Cho, Kyoung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141481/
https://www.ncbi.nlm.nih.gov/pubmed/30224682
http://dx.doi.org/10.1038/s41598-018-32352-y