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The complex underpinnings of genetic background effects

Genetic interactions between mutations and standing polymorphisms can cause mutations to show distinct phenotypic effects in different individuals. To characterize the genetic architecture of these so-called background effects, we genotype 1411 wild-type and mutant yeast cross progeny and measure th...

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Detalles Bibliográficos
Autores principales: Mullis, Martin N., Matsui, Takeshi, Schell, Rachel, Foree, Ryan, Ehrenreich, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141565/
https://www.ncbi.nlm.nih.gov/pubmed/30224702
http://dx.doi.org/10.1038/s41467-018-06023-5