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Autophagy-independent induction of LC3B through oxidative stress reveals its non-canonical role in anoikis of ovarian cancer cells

Cancer cells display abnormal redox metabolism. Autophagy, anoikis and reactive oxygen species (ROS) play a regulatory role during metastasis. LC3 is a well-known essential molecule for autophagy. Therefore, we wanted to explore the molecular interplay between autophagy, anoikis, and ROS in relation...

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Detalles Bibliográficos
Autores principales: Satyavarapu, Eswara Murali, Das, Ranjita, Mandal, Chandan, Mukhopadhyay, Asima, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141567/
https://www.ncbi.nlm.nih.gov/pubmed/30224639
http://dx.doi.org/10.1038/s41419-018-0989-8