Cargando…
Autophagy-independent induction of LC3B through oxidative stress reveals its non-canonical role in anoikis of ovarian cancer cells
Cancer cells display abnormal redox metabolism. Autophagy, anoikis and reactive oxygen species (ROS) play a regulatory role during metastasis. LC3 is a well-known essential molecule for autophagy. Therefore, we wanted to explore the molecular interplay between autophagy, anoikis, and ROS in relation...
Autores principales: | Satyavarapu, Eswara Murali, Das, Ranjita, Mandal, Chandan, Mukhopadhyay, Asima, Mandal, Chitra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141567/ https://www.ncbi.nlm.nih.gov/pubmed/30224639 http://dx.doi.org/10.1038/s41419-018-0989-8 |
Ejemplares similares
-
Desialylation of Atg5 by sialidase (Neu2) enhances autophagosome formation to induce anchorage-dependent cell death in ovarian cancer cells
por: Satyavarapu, Eswara Murali, et al.
Publicado: (2021) -
Preclinical Development of Mahanine-Enriched Fraction from Indian Spice Murraya koenigii for the Management of Cancer: Efficacy, Temperature/pH stability, Pharmacokinetics, Acute and Chronic Toxicity (14-180 Days) Studies
por: Satyavarapu, Eswara Murali, et al.
Publicado: (2020) -
Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells
por: Satyavarapu, Eswara Murali, et al.
Publicado: (2020) -
mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation
por: Maiti, Samarpan, et al.
Publicado: (2017) -
Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis
por: Roy, Saptarshi, et al.
Publicado: (2017)