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Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements

The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monot...

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Detalles Bibliográficos
Autores principales: Ramírez-Vargas, Gabriel, López-Ureña, Diana, Badilla, Adriana, Orozco-Aguilar, Josué, Murillo, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves-Olarte, Esteban, Quesada-Gómez, Carlos, Rodríguez, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141592/
https://www.ncbi.nlm.nih.gov/pubmed/30224751
http://dx.doi.org/10.1038/s41598-018-32390-6