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Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements
The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monot...
Autores principales: | Ramírez-Vargas, Gabriel, López-Ureña, Diana, Badilla, Adriana, Orozco-Aguilar, Josué, Murillo, Tatiana, Rojas, Priscilla, Riedel, Thomas, Overmann, Jörg, González, Gabriel, Chaves-Olarte, Esteban, Quesada-Gómez, Carlos, Rodríguez, César |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141592/ https://www.ncbi.nlm.nih.gov/pubmed/30224751 http://dx.doi.org/10.1038/s41598-018-32390-6 |
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