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Cre-Recombinase Dependent Germline Deletion of a Conditional Allele in the Rgs9cre Mouse Line
Cre-LoxP conditional knockout animals have become a prominent tool to understand gene function in discrete cell-types and neural circuits. However, this technology has significant limitations including off target cre-dependent recombination. The Rgs9cre strain has been used to generate a conditional...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141680/ https://www.ncbi.nlm.nih.gov/pubmed/30254571 http://dx.doi.org/10.3389/fncir.2018.00068 |