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NKG2D Ligands–Critical Targets for Cancer Immune Escape and Therapy

DNA damage, oncogene activation and excessive proliferation, chromatin modulations or oxidative stress are all important hallmarks of cancer. Interestingly, all of these abnormalities also induce a cellular stress response. By upregulating “stress-induced ligands,” damaged or transformed cells can b...

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Detalles Bibliográficos
Autores principales: Schmiedel, Dominik, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141707/
https://www.ncbi.nlm.nih.gov/pubmed/30254634
http://dx.doi.org/10.3389/fimmu.2018.02040