Cargando…
NKG2D Ligands–Critical Targets for Cancer Immune Escape and Therapy
DNA damage, oncogene activation and excessive proliferation, chromatin modulations or oxidative stress are all important hallmarks of cancer. Interestingly, all of these abnormalities also induce a cellular stress response. By upregulating “stress-induced ligands,” damaged or transformed cells can b...
Autores principales: | Schmiedel, Dominik, Mandelboim, Ofer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141707/ https://www.ncbi.nlm.nih.gov/pubmed/30254634 http://dx.doi.org/10.3389/fimmu.2018.02040 |
Ejemplares similares
-
The HHV-6A Proteins U20 and U21 Target NKG2D Ligands to Escape Immune Recognition
por: Chaouat, Abigael Eva, et al.
Publicado: (2021) -
Disarming Cellular Alarm Systems—Manipulation of Stress-Induced NKG2D Ligands by Human Herpesviruses
por: Schmiedel, Dominik, et al.
Publicado: (2017) -
Human Metapneumovirus Escapes NK Cell Recognition through the Downregulation of Stress-Induced Ligands for NKG2D
por: Diab, Mohammad, et al.
Publicado: (2020) -
The RNA binding protein IMP3 facilitates tumor immune escape by downregulating the stress-induced ligands ULPB2 and MICB
por: Schmiedel, Dominik, et al.
Publicado: (2016) -
NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment
por: Frazao, Alexandra, et al.
Publicado: (2019)