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TFPI-2 Protects Against Gram-Negative Bacterial Infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad ant...

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Detalles Bibliográficos
Autores principales: Ali, Mohamad N., Kasetty, Gopinath, Elvén, Malin, Alyafei, Saud, Jovic, Sandra, Egesten, Arne, Herwald, Heiko, Schmidtchen, Artur, Papareddy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141739/
https://www.ncbi.nlm.nih.gov/pubmed/30254643
http://dx.doi.org/10.3389/fimmu.2018.02072