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Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression

The cerebral cortex contains an enormous number of neurons, allowing it to perform highly complex neural tasks. Understanding how these neurons develop at the correct time and place and in accurate numbers constitutes a major challenge. Here, we demonstrate a novel role for Gli3, a key regulator of...

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Detalles Bibliográficos
Autores principales: Hasenpusch-Theil, Kerstin, West, Stephen, Kelman, Alexandra, Kozic, Zrinko, Horrocks, Sophie, McMahon, Andrew P., Price, David J., Mason, John O., Theil, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141774/
https://www.ncbi.nlm.nih.gov/pubmed/30093555
http://dx.doi.org/10.1242/dev.163147