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BMP- and neuropilin 1-mediated motor axon navigation relies on spastin alternative translation

Functional analyses of genes responsible for neurodegenerative disorders have unveiled crucial links between neurodegenerative processes and key developmental signalling pathways. Mutations in SPG4-encoding spastin cause hereditary spastic paraplegia (HSP). Spastin is involved in diverse cellular pr...

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Detalles Bibliográficos
Autores principales: Jardin, Nicolas, Giudicelli, François, Ten Martín, Daniel, Vitrac, Anaïs, De Gois, Stéphanie, Allison, Rachel, Houart, Corinne, Reid, Evan, Hazan, Jamilé, Fassier, Coralie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141775/
https://www.ncbi.nlm.nih.gov/pubmed/30082270
http://dx.doi.org/10.1242/dev.162701