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Effects of C2-Ceramide and Oltipraz on Hepatocyte Nuclear Factor-1 and Glutathione S-Transferase A1 in Acetaminophen-Mediated Acute Mice Liver Injury

In this study, acetaminophen (APAP)-induced acute liver injury mice model was used to investigate the effects of C2-ceramide and oltipraz on hepatocyte nuclear factor 1 (HNF-1) and glutathione S-transferase A1 (GSTA1). Notably, C2-ceramide caused alteration in mice serum transaminases and liver tiss...

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Detalles Bibliográficos
Autores principales: Ma, Xin, Chang, Yicong, Zhang, Yuanyuan, Muhammad, Ishfaq, Shi, Chenxi, Li, Rui, Li, Changwen, Li, Zhi, Lin, Yuexia, Han, Qing, Liu, Fangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141969/
https://www.ncbi.nlm.nih.gov/pubmed/30254584
http://dx.doi.org/10.3389/fphar.2018.01009