Integration of in vitro and in silico Models Using Bayesian Optimization With an Application to Stochastic Modeling of Mesenchymal 3D Cell Migration

Cellular migration plays a crucial role in many aspects of life and development. In this paper, we propose a computational model of 3D migration that is solved by means of the tau-leaping algorithm and whose parameters have been calibrated using Bayesian optimization. Our main focus is two-fold: to...

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Detalles Bibliográficos
Autores principales: Merino-Casallo, Francisco, Gomez-Benito, Maria J., Juste-Lanas, Yago, Martinez-Cantin, Ruben, Garcia-Aznar, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142046/
https://www.ncbi.nlm.nih.gov/pubmed/30271351
http://dx.doi.org/10.3389/fphys.2018.01246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142046/
https://www.ncbi.nlm.nih.gov/pubmed/30271351
http://dx.doi.org/10.3389/fphys.2018.01246

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