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Serine metabolism in the brain regulates starvation-induced sleep suppression in Drosophila melanogaster

Sleep and metabolism are physiologically and behaviorally intertwined; however, the molecular basis for their interaction remains poorly understood. Here, we identified a serine metabolic pathway as a key mediator for starvation-induced sleep suppression. Transcriptome analyses revealed that enzymes...

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Detalles Bibliográficos
Autores principales: Sonn, Jun Young, Lee, Jongbin, Sung, Min Kyung, Ri, Hwajung, Choi, Jung Kyoon, Lim, Chunghun, Choe, Joonho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142195/
https://www.ncbi.nlm.nih.gov/pubmed/29915051
http://dx.doi.org/10.1073/pnas.1719033115