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Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture

BACKGROUND: Alternative splicing, particularly through intron retention and exon skipping, is a major layer of pre-translational regulation in eukaryotes. While intron retention is believed to be the most prevalent mode across non-animal eukaryotes, animals have unusually high rates of exon skipping...

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Detalles Bibliográficos
Autores principales: Grau-Bové, Xavier, Ruiz-Trillo, Iñaki, Irimia, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142364/
https://www.ncbi.nlm.nih.gov/pubmed/30223879
http://dx.doi.org/10.1186/s13059-018-1499-9