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Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture
BACKGROUND: Alternative splicing, particularly through intron retention and exon skipping, is a major layer of pre-translational regulation in eukaryotes. While intron retention is believed to be the most prevalent mode across non-animal eukaryotes, animals have unusually high rates of exon skipping...
Autores principales: | Grau-Bové, Xavier, Ruiz-Trillo, Iñaki, Irimia, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142364/ https://www.ncbi.nlm.nih.gov/pubmed/30223879 http://dx.doi.org/10.1186/s13059-018-1499-9 |
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