Restriction enzyme digestion of host DNA enhances universal detection of parasitic pathogens in blood via targeted amplicon deep sequencing

BACKGROUND: Targeted amplicon deep sequencing (TADS) of the 16S rRNA gene is commonly used to explore and characterize bacterial microbiomes. Meanwhile, attempts to apply TADS to the detection and characterization of entire parasitic communities have been hampered since conserved regions of many con...

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Detalles Bibliográficos
Autores principales: Flaherty, Briana R., Talundzic, Eldin, Barratt, Joel, Kines, Kristine J., Olsen, Christian, Lane, Meredith, Sheth, Mili, Bradbury, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142370/
https://www.ncbi.nlm.nih.gov/pubmed/30223888
http://dx.doi.org/10.1186/s40168-018-0540-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142370/
https://www.ncbi.nlm.nih.gov/pubmed/30223888
http://dx.doi.org/10.1186/s40168-018-0540-2

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