Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction

BACKGROUND: Platelet glycoprotein Ibα (GPIbα) extracellular domain, which is part of the receptor complex GPIb-IX-V, plays an important role in tumor metastasis. However, the mechanism through which GPIbα participates in the metastatic process remains unclear. In addition, potential bleeding complic...

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Detalles Bibliográficos
Autores principales: Qi, Yingxue, Chen, Wenchun, Liang, Xinyu, Xu, Ke, Gu, Xiangyu, Wu, Fengying, Fan, Xuemei, Ren, Shengxiang, Liu, Junling, Zhang, Jun, Li, Renhao, Liu, Jianwen, Liang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142402/
https://www.ncbi.nlm.nih.gov/pubmed/30223883
http://dx.doi.org/10.1186/s13045-018-0659-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142402/
https://www.ncbi.nlm.nih.gov/pubmed/30223883
http://dx.doi.org/10.1186/s13045-018-0659-4

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