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Common DNA Variants Accurately Rank an Individual of Extreme Height

Polygenic scores (or genetic risk scores) quantify the aggregate of small effects from many common genetic loci that have been associated with a trait through genome-wide association. Polygenic scores were first used successfully in schizophrenia and have since been applied to multiple phenotypes in...

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Detalles Bibliográficos
Autores principales: Sexton, Corinne E., Ebbert, Mark T. W., Miller, Ryan H., Ferrel, Meganne, Tschanz, Jo Ann T., Corcoran, Christopher D., Ridge, Perry G., Kauwe, John S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142724/
https://www.ncbi.nlm.nih.gov/pubmed/30255029
http://dx.doi.org/10.1155/2018/5121540