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Dynamic DNA Methylation Changes of Tbx21 and Rorc during Experimental Autoimmune Uveitis in Mice

The key transcription factors of T helper cell subpopulations, including T-bet, GATA3, RORγt, and Foxp3 are involved in various autoimmune diseases. Whether methylation of these master transcription factors is associated with the development of experimental autoimmune uveitis (EAU) and the possible...

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Detalles Bibliográficos
Autores principales: Qiu, Yiguo, Zhu, Yunyun, Yu, Hongsong, Zhou, Chunjiang, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142759/
https://www.ncbi.nlm.nih.gov/pubmed/30254507
http://dx.doi.org/10.1155/2018/9129163