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A novel and practical asymmetric synthesis of eptazocine hydrobromide

In order to prepare eptazocine hydrobromide effectively, a novel, mild and practical asymmetric process was developed starting from 1-methyl-7-methoxy-2-tetralone under the catalysis of N-(p-trifluoromethylbenzyl)cinchonidinium bromide. The reaction conditions were optimized to obtain the product in...

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Detalles Bibliográficos
Autores principales: Li, Ruipeng, Liu, Zhenren, Chen, Liang, Pan, Jing, Lin, Kuaile, Zhou, Weicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142761/
https://www.ncbi.nlm.nih.gov/pubmed/30254698
http://dx.doi.org/10.3762/bjoc.14.209