HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

High mobility group box protein 1 (HMGB1) is a ubiquitous nuclear protein released by glia and neurons upon inflammasome activation and activates receptor for advanced glycation end products (RAGE) and toll-like receptor (TLR) 4 on the target cells. HMGB1/TLR4 axis is a key initiator of neuroinflamm...

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Detalles Bibliográficos
Autores principales: Paudel, Yam Nath, Shaikh, Mohd. Farooq, Chakraborti, Ayanabha, Kumari, Yatinesh, Aledo-Serrano, Ángel, Aleksovska, Katina, Alvim, Marina Koutsodontis Machado, Othman, Iekhsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142787/
https://www.ncbi.nlm.nih.gov/pubmed/30271319
http://dx.doi.org/10.3389/fnins.2018.00628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142787/
https://www.ncbi.nlm.nih.gov/pubmed/30271319
http://dx.doi.org/10.3389/fnins.2018.00628

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