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Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro

BACKGROUND: Oxymatrine, a component extracted from the traditional Chinese herb Sophora japonica (Sophora flavescens Ait.), has various pharmacological effects, especially on the cardiovascular system. However, its cardiac protection effects and the underlying mechanism are still poorly understood....

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Detalles Bibliográficos
Autores principales: Zhao, Linglu, Xu, Yini, Tao, Ling, Yang, Yu, Shen, Xiangchun, Li, Ling, Luo, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142867/
https://www.ncbi.nlm.nih.gov/pubmed/30196308
http://dx.doi.org/10.12659/MSM.910142