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Vitamin D, FOXO3a, and Sirtuin1 in Hashimoto's Thyroiditis and Differentiated Thyroid Cancer

Background: Protective effects of vitamin D have been reported in autoimmune and malignant thyroid diseases, though little is known about the underlying mechanism. Sirtuin 1 histon deacethylase (SIRT1) links the vitamin D pathway with regulation of transcription factor FOXO3a, a key player in cell c...

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Detalles Bibliográficos
Autores principales: Roehlen, Natascha, Doering, Claudia, Hansmann, Martin-Leo, Gruenwald, Frank, Vorlaender, Christian, Bechstein, Wolf Otto, Holzer, Katharina, Badenhoop, Klaus, Penna-Martinez, Marissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142903/
https://www.ncbi.nlm.nih.gov/pubmed/30271381
http://dx.doi.org/10.3389/fendo.2018.00527