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Oscillatory IL-2 stimulus reveals pertinent signaling timescales of T cell responsiveness
Cell response to extracellular ligand is affected not only by ligand availability, but also by pre-existing cell-to-cell variability that enables a range of responses within a cell population. We developed a computational model that incorporates cell heterogeneity in order to investigate Jurkat T ce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143248/ https://www.ncbi.nlm.nih.gov/pubmed/30226854 http://dx.doi.org/10.1371/journal.pone.0203759 |