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Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness

Merkel cell carcinoma (MCC) is an aggressive skin cancer with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) is recognised as the causative factor in the majority of MCC cases. The MCPyV small tumour antigen (ST) is considered to be the main viral transforming fact...

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Detalles Bibliográficos
Autores principales: Nwogu, Nnenna, Boyne, James R., Dobson, Samuel J., Poterlowicz, Krzysztof, Blair, G. Eric, Macdonald, Andrew, Mankouri, Jamel, Whitehouse, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143273/
https://www.ncbi.nlm.nih.gov/pubmed/30188954
http://dx.doi.org/10.1371/journal.ppat.1007276