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FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination

FGF signaling is a potent inducer of lacrimal gland development in the eye, capable of transforming the corneal epithelium into glandular tissues. Here, we show that genetic ablation of the Pea3 family of transcription factors not only disrupted the ductal elongation and branching of the lacrimal gl...

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Detalles Bibliográficos
Autores principales: Garg, Ankur, Hannan, Abdul, Wang, Qian, Collins, Tamica, Teng, Siying, Bansal, Mukesh, Zhong, Jian, Xu, Keli, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143274/
https://www.ncbi.nlm.nih.gov/pubmed/30188892
http://dx.doi.org/10.1371/journal.pgen.1007660