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Subcellular Protein Labeling by a Spatially Restricted Arylamine N-Acetyltransferase

[Image: see text] Mapping proteins at a specific subcellular location is essential to gaining detailed insight on local protein dynamics. We have developed an enzymatic strategy to label proteins on a subcellular level using arylamine N-acetyltransferase (NAT). The NAT enzyme activates an arylhydrox...

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Detalles Bibliográficos
Autores principales: Kleinpenning, Fleur, Eising, Selma, Berkenbosch, Tim, Garzero, Veronica, Schaart, Judith M., Bonger, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143282/
https://www.ncbi.nlm.nih.gov/pubmed/29851463
http://dx.doi.org/10.1021/acschembio.8b00178