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Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system

The intestinal lymphatic system plays an important role in the pathophysiology of multiple diseases including lymphomas, cancer metastasis, autoimmune diseases, and human immunodeficiency virus (HIV) infection. It is thus an important compartment for delivery of drugs in order to treat diseases asso...

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Detalles Bibliográficos
Autores principales: Lee, Jong Bong, Zgair, Atheer, Malec, Jed, Kim, Tae Hwan, Kim, Min Gi, Ali, Joseph, Qin, Chaolong, Feng, Wanshan, Chiang, Manting, Gao, Xizhe, Voronin, Gregory, Garces, Aimie E., Lau, Chun Long, Chan, Ting-Hoi, Hume, Amy, McIntosh, Tecashanell M., Soukarieh, Fadi, Al-Hayali, Mohammed, Cipolla, Elena, Collins, Hilary M., Heery, David M., Shin, Beom Soo, Yoo, Sun Dong, Kagan, Leonid, Stocks, Michael J., Bradshaw, Tracey D., Fischer, Peter M., Gershkovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143478/
https://www.ncbi.nlm.nih.gov/pubmed/30016732
http://dx.doi.org/10.1016/j.jconrel.2018.07.022