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Induction and maintenance of a phenotypically heterogeneous lung tissue-resident CD4(+) T cell population following BCG immunisation

Tuberculosis (TB) is the biggest cause of human mortality from an infectious disease. The only vaccine currently available, bacille Calmette-Guérin (BCG), demonstrates some protection against disseminated disease in childhood but very variable efficacy against pulmonary disease in adults. A greater...

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Detalles Bibliográficos
Autores principales: Bull, Naomi C., Kaveh, Daryan A., Garcia-Pelayo, M.C., Stylianou, Elena, McShane, Helen, Hogarth, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143486/
https://www.ncbi.nlm.nih.gov/pubmed/30097220
http://dx.doi.org/10.1016/j.vaccine.2018.07.035