Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis

Mitohormesis is an adaptive response induced by a mild mitochondrial stress that promotes longevity and metabolic health in different organisms. This mechanism has been proposed as the cause of the increase in the survival in Coq7(+/−) (Mclk1(+/−)) mice, which show hepatic reduction of COQ7, early m...

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Detalles Bibliográficos
Autores principales: Rodríguez-Hidalgo, María, Luna-Sánchez, Marta, Hidalgo-Gutiérrez, Agustín, Barriocanal-Casado, Eliana, Mascaraque, Cristina, Acuña-Castroviejo, Darío, Rivera, Margarita, Escames, Germaine, López, Luis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522/
https://www.ncbi.nlm.nih.gov/pubmed/30228311
http://dx.doi.org/10.1038/s41598-018-32190-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522/
https://www.ncbi.nlm.nih.gov/pubmed/30228311
http://dx.doi.org/10.1038/s41598-018-32190-y

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