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TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells
TMCO1 (transmembrane and coiled-coil domains 1) is an endoplasmic reticulum (ER) transmembrane protein that actively prevents Ca(2+) stores from overfilling. To characterize its physiological function(s), we generated Tmco1(−/−) knockout (KO) mice. In addition to the main clinical features of human...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143536/ https://www.ncbi.nlm.nih.gov/pubmed/29467381 http://dx.doi.org/10.1038/s41418-018-0067-x |