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Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe the synthesis and thorough characterization of bicyclic th...

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Detalles Bibliográficos
Autores principales: Lawson, Christopher P., Füchtbauer, Anders F., Wranne, Moa S., Giraud, Tristan, Floyd, Thomas, Dumat, Blaise, Andersen, Nicolai K., H. El-Sagheer, Afaf, Brown, Tom, Gradén, Henrik, Wilhelmsson, L. Marcus, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143597/
https://www.ncbi.nlm.nih.gov/pubmed/30228309
http://dx.doi.org/10.1038/s41598-018-31897-2