Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest

Recently, functional connections between S-adenosylhomocysteine hydrolase (AHCY) activity and cancer have been reported. As the properties of AHCY include the hydrolysis of S-adenosylhomocysteine and maintenance of the cellular methylation potential, the connection between AHCY and cancer is not obv...

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Detalles Bibliográficos
Autores principales: Belužić, Lucija, Grbeša, Ivana, Belužić, Robert, Park, Jong Hoon, Kong, Hyun Kyung, Kopjar, Nevenka, Espadas, Guadalupe, Sabidó, Eduard, Lepur, Adriana, Rokić, Filip, Jerić, Ivanka, Brkljačić, Lidija, Vugrek, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143609/
https://www.ncbi.nlm.nih.gov/pubmed/30228286
http://dx.doi.org/10.1038/s41598-018-32356-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143609/
https://www.ncbi.nlm.nih.gov/pubmed/30228286
http://dx.doi.org/10.1038/s41598-018-32356-8

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