A high throughput screen for next-generation leads targeting malaria parasite transmission

Spread of parasite resistance to artemisinin threatens current frontline antimalarial therapies, highlighting the need for new drugs with alternative modes of action. Since only 0.2–1% of asexual parasites differentiate into sexual, transmission-competent forms, targeting this natural bottleneck pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Delves, Michael J., Miguel-Blanco, Celia, Matthews, Holly, Molina, Irene, Ruecker, Andrea, Yahiya, Sabrina, Straschil, Ursula, Abraham, Matthew, León, María Luisa, Fischer, Oliver J., Rueda-Zubiaurre, Ainoa, Brandt, Jochen R., Cortés, Álvaro, Barnard, Anna, Fuchter, Matthew J., Calderón, Félix, Winzeler, Elizabeth A., Sinden, Robert E., Herreros, Esperanza, Gamo, Francisco J., Baum, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143625/
https://www.ncbi.nlm.nih.gov/pubmed/30228275
http://dx.doi.org/10.1038/s41467-018-05777-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143625/
https://www.ncbi.nlm.nih.gov/pubmed/30228275
http://dx.doi.org/10.1038/s41467-018-05777-2

Ejemplares similares