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Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance

Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has increased metastatic ability. Here, we charac...

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Detalles Bibliográficos
Autores principales: Chiou, Shin-Heng, Dorsch, Madeleine, Kusch, Eva, Naranjo, Santiago, Kozak, Margaret M., Koong, Albert C., Winslow, Monte M., Grüner, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143627/
https://www.ncbi.nlm.nih.gov/pubmed/30228296
http://dx.doi.org/10.1038/s41598-018-32159-x